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Darren M. Smith, MD, FACS

How Long Does Botox Last?

March 2, 2023

How Long Does Botox Last?

Botox is an FDA-approved, effective treatment to help reduce the appearance of wrinkles. Botox injections block specific chemical signals from nerves to the muscles, causing your muscles to relax and soften instead of contract.

Botox Overview

For cosmetic use, Botox can temporarily improve the appearance of certain lines associated with muscle activity, as described in the Botox Cosmetic prescribing information. Botox also has separately labeled medical uses in adults, including headache prevention for chronic migraine, treatment of cervical dystonia (a neck muscle condition), and severe underarm sweating not adequately controlled by topical treatments.

The average treatment takes around 15 minutes. Most people can return to everyday activities immediately, as the American Academy of Dermatology explains, although bruising, swelling or soreness can occur. Follow your clinician's aftercare instructions. You can receive injections on your lunch break. Typically, Botox results last between three and four months. There isn't a one-size-fits-all approach to Botox injections. Your Botox treatment with Dr. Smith will be tailored to your unique needs and goals.

How Long Does Botox Take to work?

It typically takes two weeks for Botox to fully set in. However, you may begin to see early results within three to five days. Once completely set, it can last anywhere from three to four months, though some patients will see their Botox lasting for more or less time than this.

Botox's effects are temporary. Its prescribing information explains that it reduces nerve signaling to treated muscles; nerve connections can gradually recover. A nonrandomized study of 60 women followed for 90 days found shorter-lasting forehead and frown-line effects in moderate- and high-activity groups than in the low-activity group. The active groups practiced CrossFit, and wrinkle severity differed between groups at baseline, so these findings may not apply to every exercise routine. The study did not establish whether active patients need a higher dose. Discuss your individual response with your clinician.

How Long Does Botox Last?

Botox lasts three to four months. That said, there are a few factors that can contribute to the longevity of your injections. For example, the injection site and the amount of Botox injected can affect how long it lasts.

Other factors can influence the effectiveness as well, including:

  • Your age
  • Your skin's elasticity
  • Wrinkle depth
  • Individual treatment response
  • Physical activity level (evidence is limited and may not apply to every routine)
  • Facial expressions

Botox results are temporary, and their duration varies. The considerations below address skin health, aftercare and the limits of research on treatment response.

Can You Make Botox Last Longer?

Some studies have reported benefits with particular supplements or skin-care formulas used alongside botulinum toxin, but the products and outcomes studied differ. Research on exercise also concerns specific patient groups and does not establish a rule for every routine. The findings do not guarantee longer-lasting Botox results. The five considerations below cover skin health, aftercare and treatment questions to discuss with your clinician.

5 Considerations for Skin Health and Botox Treatment Planning

#1. Avoid Sun Damage

Sun exposure can accelerate skin aging. The American Academy of Dermatology recommends daily broad-spectrum sunscreen with SPF 30 or higher and avoiding tanning. An observational study of 523 women found higher botulinum toxin dose requirements for frown lines in a high-sun climate group than in a low-sun group. It compared climates rather than testing sunscreen and did not measure how long results lasted. Sun protection supports skin health, but this study does not establish that sunscreen will extend your Botox results or reduce your dose.

#2. Don't Smoke

Smoking contributes to premature wrinkles, as the American Academy of Dermatology explains. If you smoke, ask your clinician for help quitting. FDA-approved nicotine replacement medicines can help adults stop smoking and differ from cigarettes and vaping products; discuss which option is appropriate for you. Quitting is worthwhile for your health, but longer Botox results or a lower dose should not be promised. Treatment also depends on the type of wrinkle: the BOTOX Cosmetic prescribing information includes muscle-related lines at the outer corners of the eyes. Ask your clinician which lines may respond and what treatment is suitable for you.

#3. Avoid Rubbing Your Face

Don't tug, pull, or rub your face for 1 week after Botox injections. The American Academy of Dermatology advises avoiding rubbing or massage to limit unwanted spread. We also recommend that our patients refrain from energy-based treatments, like Morpheus8 for 1 week after Botox. Findings vary by procedure: a 19-person study found no observed loss of effect at two weeks after selected nonablative devices were used immediately after toxin. A retrospective 45-woman comparison found less wrinkle improvement at four weeks than toxin alone when radiofrequency microneedling came before toxin and injections followed immediately. These limited findings do not establish a general rule that facials or devices accelerate Botox metabolism. Confirm the timing of exfoliation, facials and additional procedures with your clinician.

#4. Update Your Skincare Routine

Moisturizer helps retain water in the skin and can soften the appearance of some fine lines, as the American Academy of Dermatology explains. A manufacturer-funded randomized study of 63 women found better wrinkle and skin-quality scores over 24 weeks with one multi-ingredient hyaluronic acid serum plus Dysport than with Dysport alone. These results suggest a complementary benefit from that particular formula. They do not establish that every moisturizer, topical collagen product or extra water intake will prolong Botox results or reduce the dose needed. Discuss suitable products and your individual treatment plan with your clinician.

#5. Eat a Proper Diet

A balanced diet supports your nutritional needs, but zinc supplements should not be treated as a guaranteed way to make Botox last longer. A 2012 pilot trial involving 77 patients reported longer botulinum toxin effects with zinc plus phytase, an enzyme. The trial included several toxin products and treatment indications, and ended early after its treatment assignments became apparent. These findings do not establish that every zinc supplement will prolong cosmetic Botox results. Ask your clinician before adding a supplement. The NIH Office of Dietary Supplements notes that excessive zinc can cause adverse effects and interfere with copper absorption, and that zinc can interact with some medications.

Botox Maintenance: How Often Can You Get Botox?

The recommended treatment for Botox injections is once every three to four months. However, some patients may benefit from small touch-ups between treatments to tweak their results. We provide these maintenance treatments at no charge. Patients who receive Botox treatments regularly may be able to go for longer periods between injections. The BOTOX Cosmetic prescribing information notes that treatment at intervals shorter than three months has not been clinically evaluated for safety or effectiveness. Discuss the timing and suitability of any repeat injection, including a touch-up, with your treating physician.

Safe Botox treatment depends on appropriate patient selection, dosing and injection technique, as well as the treating clinician's knowledge of the relevant anatomy. Repeat treatment requires an individual review of your health, medications and response to prior injections. The prescribing information lists risks including headache and eyelid or brow drooping, and warns about potentially serious swallowing or breathing difficulties. Seek immediate medical care for difficulty breathing, swallowing or speaking after treatment. Discuss the benefits and risks of continued treatment with your clinician.

Looking for Botox in NYC?

Get in touch with Dr. Darren Smith's office for more information. In addition to Botox, Dr. Smith can discuss other ways to reverse signs of aging with top-of-the-line cosmetic treatments like a brow or facelift for intensive rejuvenation.