Darren M. Smith MD. FACS

Dr. Smith is not offering AlloClae at this time.

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AlloClae™ NYC

Are you seeking a non-surgical approach to restore volume and refine your body contours?

AlloClae™ is designed to provide a natural, long-lasting solution that helps you achieve beautiful, contoured results using purified human donor fat. Dr. Darren Smith, a board-certified plastic surgeon with extensive expertise in regenerative aesthetics, brings this cutting-edge, bio-integrative technology to NYC.

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Before & After: AlloClae™

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Explore our gallery of real patient results. These before-and-after photos reflect the life-changing outcomes of plastic surgery performed by Dr. Smith.
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The procedure was virtually painless and I love my results. Dr. Smith and his team were there every step of the way. I could not be happier with my decision to go with this practice for AlloClae.”!

L C

What is AlloClae™?

AlloClae™ is a volume enhancement treatment derived from purified human donor fat. It is a structural allogenic adipose filler designed to restore natural volume and enhance body contours by building volume with fat, stimulating collagen production, and rejuvenating tissues for long-lasting, natural-looking results.
This bio-integrative approach helps restore volume in both facial and body areas, enhancing outcomes in breast augmentation, buttock contouring, facial rejuvenation, and more.
Dr. Darren Smith is recognized for his expertise in using this innovative treatment, offering personalized, high-quality care that enables you to achieve your aesthetic goals through a natural, non-surgical approach.

How Does AlloClae™ Work at Dr. Darren Smith’s Clinic?

For every AlloClae™ procedure, Dr. Darren Smith offers a precise and personalized approach targeted to your unique body. This is a cutting-edge approach unique to Dr. Smith’s practice derived from his extensive training as a board-certified plastic surgeon and deep experience with fat biology from three years spent in a tissue engineering laboratory.
  1. Consultation and 3D Imaging: Dr. Smith will discuss your goals and develop a personalized treatment plan for you, accompanied by a 3D imaging procedure for a visual simulation of your results.
  2. Fat Processing and Purification: The donor fat undergoes a 5-step process that isolates, refines, and terminally sterilizes the adipose tissue. Dr. Smith will customize your AlloClae™ treatment by integrating your own donor fat when appropriate.
  3. Injection and Integration: On the day of your procedure, Dr. Smith will inject the appropriate volume of AlloClae™ into the designated areas. The product is available in 12.5cc vials sold in 25cc increments. Many cases can be performed with local anesthesia. Larger cases are done with general anesthesia or IV sedation administered by our board-certified anesthesiologist.
  4. Recovery and Results: After the procedure, expect mild swelling and bruising, which typically resolves within 1-2 weeks. Full results become visible within 6 months.
  5. Follow-Up Appointments: Dr. Smith’s team will schedule regular follow-up appointments to ensure your recovery is progressing smoothly.

AlloClae™ vs. Traditional Fillers and Fat Grafting

Compared to traditional fillers and fat grafting, AlloClae™ offers a more natural and long-lasting solution for volume restoration for those without sufficient fat of their own.

Here’s a quick comparison guide to know which procedure suits your needs:
FeatureAlloClae™Traditional FillersFat Grafting
Harvest RequiredNoNoYes
InvasivenessNon-surgicalNon-surgicalSurgical
LongevityLong-lasting (years)Short-term (months)Long-lasting (depends on fat survival)
Tissue CompatibilityHighly compatibleLimited tissue integrationNatural tissue compatibility
Volume CapacityHighLowHigh
Main BenefitNatural volume restorationQuick cosmetic changesCustomized, natural fat transfer
PredictabilityVery predictableLess predictableCan vary depending on fat survival

What Are the Benefits of AlloClae™?

AlloClae™ is the medical-grade, non-surgical solution for those seeking fast, safe, and relatively pain-free treatment. Unlike other injectables like Juvederm, which often require more frequent touch-ups, AlloClae™ provides long-lasting results that can last for years instead of months.

  • Natural volume restoration without surgery
  • Bio-integrative technology that stimulates collagen
  • Long-lasting results (years, not months)
  • No donor site harvesting required
  • Versatile applications for face and body
  • Minimal downtime and recovery
  • Natural-looking, undetectable results
  • FDA-regulated HCT/P safety standards
AlloClae™ requires a commitment to following post-treatment care protocols. Dr. Darren Smith will provide personalized recovery instructions to help you achieve the best possible results after the procedure.
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Advanced Applications of AlloClae™ at Dr. Darren Smith’s Clinic

  • Natural Breast Enhancement With or Without Implants
  • Body Contouring After GLP-1 (Mounjaro or Ozemipic) weight loss
  • Athletic BBL and Buttock Contouring
  • Post-Liposuction Contour Correction
  • Facial Volume Restoration
  • High definition liposculpture
  • Cellulite Reduction

Natural Breast Enhancement Without Implants

Fat transfer-based breast augmentation has emerged as a viable alternative to those seeking a modest increase in breast size without implants. Patients without sufficient fat for use as a donor site have until now not been able to benefit from this approach. AlloClae™ allows patients without fat available for use as a graft to enjoy implant-free breast augmentation for the first time. It can also be used to correct asymmetries and implant irregularities to help patients achieve a natural, harmonious, and balanced breast contour.

Body Contouring After GLP-1 (Mounjaro or Ozempic) Weight Loss

These exciting weight loss medications are a game-changer in helping you shed excess weight. However, you cannot decide where the volume loss occurs. Patients may find undesirable effects from decreased fat volume in certain areas, especially in the form of “Ozempic breasts” and “Ozempic butt” (think “Ozempic Face” but for the breasts and buttocks). While traditional fat transfer is an appealing treatment strategy for these issues, patients who have lost significant amounts of weight with GLP-1 medications often do not have sufficient fat of their own to use as donor fat. AlloClae™is extremely beneficial in these scenarios as an off-the-shelf fat graft alternative as it mitigates the need for a donor site.

Athletic BBL and Buttock Contouring

For those lacking sufficient donor fat, AlloClae™ creates a natural, athletic buttock contour and addresses hip dips. Similar to a “Skinny BBL,” the AlloClae™ can enhance projection and volume without the need for extensive fat harvesting. This is ideal for individuals with a lower BMI of typically less than 25.

Post-Liposuction Contour Correction

AlloClae™ can correct irregularities and indentations from liposuction, such as facial volume loss and “Ozempic butts.” This treatment solves challenges in post-liposuction contouring by restoring volume and smoothing the body for a more balanced, harmonious silhouette.

Facial Volume Restoration

AlloClae™ can help restore volume in areas like the cheeks, temples, and under-eye hollows. It provides a natural-looking rejuvenation that enables patients to restore youthfulness from long-lasting facial enhancement. This application will be available with a version of the product to be released in the near future. The present iteration of AlloClae is too structured for reliable use in the face.

Cellulite Treatment

Cellulite has long evaded effective management. We can now leverage AlloClae™ as part of a customized approach to effectively address cellulite once and for all. Specifically, AlloClae™ can be combined with Aveli to enhance efficacy in treating dimpling cellulite. BodyTite can be added when wavy cellulite is part of the picture as well.

Other Applications

AlloClae™ is also effective for hand rejuvenation, traumatic contour irregularities, and post-weight loss volume restoration. This treatment is specifically beneficial for individuals seeking to enhance volume in areas affected by aging or weight fluctuations.

Ideal Candidates for AlloClae™

AlloClae™ is ideal for patients seeking natural, long-lasting volume enhancement through a non-surgical procedure, including:
  • Nonsmokers who are in good health and have realistic expectations
  • Patients with stable weight but have a low BMI, typically within 18-25
  • Individuals who lack sufficient donor fat for traditional fat transfer methods
  • Post-weight loss patients needing volume restoration
  • Those with previous liposuction or aging patients with facial volume loss
  • Individuals seeking volume enhancement in areas where natural fat exists, such as the breasts, glutes, and hips
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Real Patient Testimonials

“I Should Never Consider Another Plastic Surgeon!”

My experience with Dr. Darren Smith and his staff made it obvious that I should never consider another plastic surgeon! I had several consultations with other cosmetic surgeons for a breast lift procedure before making the indisputable choice to go with Dr. Darren Smith.

S K

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Why Choose Dr. Darren Smith for AlloClae™?

You deserve the expertise of a surgeon who prioritizes precision, results, and your comfort. Dr. Darren Smith follows a user-centric approach, offering a combination of elite training, advanced techniques, and a luxury, wellness-oriented experience to ensure you receive high-quality, patient-focused care.

Surgeon’s Credentials & Expertise

Dr. Darren Smith is trusted by patients with high-profile and complex cases. He is recognized for his advanced training in both aesthetic and craniofacial surgery as well as his extensive tissue engineering background; this experience allows Dr. Smith to deliver AlloClae™ with a unique degree of expertise for optimal outcomes. He is one of the few surgeons in NYC and the world who can who can leverage this level of experience to design and execute next-level AlloClae™ treatments. He offers advanced techniques like synergistic fat grafting, a combination of AlloClae™ and autologous fat transfer, along with Vectra 3D imaging guidance to ensure each procedure is tailored for optimal results.

Luxury, Concierge Experience

Dr. Darren Smith focuses on providing world-class, personalized care and an exclusive experience for every discerning patient. Experience a luxurious, concierge experience in a state-of-the-art private operating suite in the Ritz Tower to ensure comfort, privacy, and precision in all treatments. Every detail of your treatment plan is expert-backed and curated to meet your specific needs.

Discover how AlloClae™ can help you achieve your aesthetic goals with a personalized, luxury experience. Call us at +1 (212) 633-0627 to schedule a consultation with Dr. Darren Smith today.

Schedule an AlloClae™ Consultation with Dr. Darren Smith

If you’re considering AlloClae™ or other body contouring treatments, schedule a consultation with Dr. Darren Smith today to discuss your options.
Dr. Smith will help you find the best solution tailored to your aesthetic alignment and medical history.
111 East 57th Street, New York, NY, 10022

FAQs About AlloClae™

AlloClae™ in the Heart of New York City

Dr. Smith’s practice sits in Manhattan’s Upper East Side, steps from Central Park and at the center of New York City’s most established medical corridor. The office welcomes patients from across the five boroughs, the tri-state area, and well beyond.

Choosing where you have surgery matters as much as choosing who performs it. New Yorkers come to Dr. Smith because his work reflects the city itself: refined, exacting, and never one-size-fits-all. Whether you’re a lifelong New Yorker or traveling in for a consultation, you’ll find a practice that treats every patient with precision and discretion that have made Manhattan a destination for plastic surgery patients from around the world.

Belvedere Castle in Central Park, New York City — steps from Dr. Smith's Manhattan practice

Schedule an AlloClae™ Consultation with Dr. Darren Smith

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“Within the first couple of minutes of meeting him, I knew he was the doctor for me.”

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